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Endometriosis Treatment Options in Asia: What You Should Know

Endometriosis is a chronic condition that affects reproductive-age females, where tissue similar to the lining of the uterus grows outside the uterus. It affects approximately one in ten women in their childbearing years and is a prevalent condition both globally and in Singapore [1]. 

Symptoms of endometriosis commonly include painful periods, heavy menstrual bleeding, pelvic pain, and in some cases, infertility. This condition can significantly reduce quality of life, causing not only pain but also fatigue, anxiety, and depression. For some women, the pain can interfere with daily activities, making it difficult to attend work or school. Pain during sex can also disrupt intimacy, affecting both individuals and their partners. 

Endometriosis is a systemic condition that can affect not only the uterus but also the ovaries, vagina, rectum, and other pelvic organs. Early treatment is essential to improve both overall health and reproductive outcomes for women living with the condition. With appropriate medical care,  including medication, lifestyle adjustments, or surgical treatments, many women experience significant relief from symptoms and enjoy an improved quality of life.

Keep reading to find out more about endometriosis and treatment options in Asia.

Pain caused by endometriosis can interfere with daily activities, making it difficult to attend work or school. 

Understanding Endometriosis

What is Endometriosis?

Endometriosis is an inflammatory condition where tissue similar to the lining of the uterus (endometrium) grows outside the uterus. These growths are often found on the ovaries, fallopian tubes, bladder, intestines, and other pelvic organs. When they respond to hormonal changes during the menstrual cycle, they often cause inflammation, pain, and scarring over time. 

Endometriosis can also damage the fallopian tubes, interfere with embryo implantation, reduce egg quality, and diminish ovarian reserve, ultimately affecting fertility. 

What Causes Endometriosis?

The exact cause of endometriosis remains unknown, but some theories [2] include:

  • Retrograde menstruation: Occurs when menstrual blood flows backward through the fallopian tubes into the pelvic cavity, carrying endometrial cells. These cells can attach to the pelvic walls and organs, where they grow and thicken with each menstrual cycle.
  • Transformed peritoneal cells: Research suggests that hormones or immune factors may cause peritoneal cells, which line the inner abdomen, to transform into cells resembling those that line the uterus.
  • Embryonic cell changes: Hormones such as estrogen may trigger embryonic cells to transform into endometrial-like tissue, contributing to growths during puberty.
  • Complications from surgery: Endometrial cells can attach to scar tissue formed after abdominal surgeries, such as a cesarean, leading to endometriosis.
  • Endometrial cell transport: Blood vessels or the tissue fluid system may transport endometrial cells to other areas of the body, causing them to implant and grow in locations outside the uterus.
  • Immune system dysfunction: Immune system issues may cause endometrial-like tissue to implant and grow.

Several risk factors of endometriosis make some women more prone to developing the condition. These include:

  • Never giving birth
  • Starting menstruation at an early age
  • Entering menopause at a later age
  • Short menstrual cycles (less than 27 days)
  • Heavy periods lasting more than seven days
  • Higher estrogen levels or prolonged estrogen exposure
  • Low body mass index (BMI)
  • A family history of endometriosis 

Common Symptoms of Endometriosis 

Endometriosis symptoms vary among individuals, and the severity of symptoms does not always correlate [3] with the extent of the disease. Some women with severe endometriosis may have mild symptoms, and vice versa. Some people with endometriosis do not experience symptoms. For those that they do, they often include:

  • Chronic pelvic pain, especially before and during menstruation.
  • Dysmenorrhea (painful, often debilitating periods).
  • Dyspareunia (experiencing pain during or after intercourse).
  • Infertility
  • Pain and discomfort during bowel movements, bloating, or urinary issues when menstruating. 
  • Fatigue, diarrhea, constipation, bloating, or nausea before or during menstruation. 
  • Heavy or abnormal bleeding between periods. 
Endometriosis often causes symptoms that interfere with daily life, leading many to seek treatment.

Diagnosis Methods in Asia

Diagnosing endometriosis can be challenging and often delayed due to normalisation of menstrual pain and lack of awareness. In Asia, common diagnostic methods include:

  • Clinical history: Taking notes of the patient’s symptoms and medical history. 
  • Pelvic examination: To detect cysts or tenderness.
  • Imaging techniques:
  • Ultrasound (transvaginal or abdominal): Used for identifying ovarian endometriomas.
  • MRI Scans: Used for visualising deep infiltrating endometriosis.
  • Laparoscopy (minimally invasive surgery): A common diagnostic method that allows direct visualisation and biopsy of growths and lesions.

Non-Surgical Treatment Options for Endometriosis in Asia

Many women with endometriosis seek non-surgical treatments to alleviate symptoms, improve quality of life, and preserve fertility. In Asia, a range of non-surgical treatment options are available, including medication, alternative therapies, and lifestyle adjustments. These treatments offer personalised approaches to managing the condition, depending on the severity of symptoms and individual preferences. Here are some common non-surgical treatment options: 

  • Oral contraceptives

Oral contraceptives, including birth control pills and hormonal treatments, are commonly used to regulate menstrual cycles, reduce pain, and suppress the growth of endometrial tissue. These treatments help control symptoms, especially in mild cases.

  • Pain relief

Non-prescription pain relievers such as NSAIDs are often used to manage pelvic pain and menstrual cramps, offering short-term relief from symptoms. 

  • Diet and lifestyle changes 

Anti-inflammatory diets [4], which are rich in omega-3 fatty acids, fruits, and vegetables, may help reduce inflammation and pain. Exercise and stress management techniques, such as yoga or meditation, can also aid in symptom management.

These approaches primarily manage symptoms rather than cure the condition, as there are limitations to non-surgical treatments. For example, hormonal treatments may not be suitable for women trying to conceive or those who experience side effects. 

If symptoms persist despite non-surgical treatments, or if there are concerns about fertility, surgical options such as laparoscopy and robotic gynaecological surgery may be necessary to remove severe endometrial growths.

Pain management, such as heat therapy and pain relievers, helps to manage symptoms but does not treat the underlying cause of endometriosis.

Surgical Treatment Options for Endometriosis in Asia

For women with severe endometriosis or those unresponsive to non-surgical treatments, surgery is often required to remove endometrial tissue, alleviate pain, and preserve fertility. In Asia, surgical options like laparoscopy and robotic gynaecological surgery offer solutions with varying benefits depending on the severity of the condition and the patient’s goals. 

Types of Surgery for Endometriosis: 

  • Laparoscopy (Minimally Invasive Surgery): Laparoscopy involves small incisions through which a camera and surgical tools are inserted to remove or destroy endometrial tissue. This procedure is less invasive, allows for faster recovery, and is often used for both diagnosis and treatment.
  • Hysterectomy: This involves the removal of the uterus, and in some cases, the ovaries. It is typically considered for women who no longer wish to have children and have not found relief through other treatments. While effective in reducing symptoms, a hysterectomy may not cure endometriosis completely.
  • Robotic gynaecological surgery: Robotic gynaecological surgery is a minimally invasive surgery [5] that involves using robotic arms controlled by the surgeon for precision. This method allows surgeons to remove endometrial tissue while minimising damage to surrounding organs. One of the primary goals of this surgery is to preserve fertility. The precision of the robotic system allows surgeons to carefully remove endometrial growths while sparing healthy tissue, improving the chances of natural conception or assisted reproductive techniques.

How to Choose the Right Gynaecologic Surgeon for Endometriosis Treatment in Asia

Choosing the right gynaecologic surgeon for endometriosis treatment is essential for achieving the best outcomes. When selecting a surgeon, it's important to consider the severity of your symptoms, fertility goals, and access to high-quality care. If robotic gynaecological surgery is the recommended treatment, it’s ideal to choose a surgeon with experience and expertise in the field. 

A skilled surgeon usually takes a holistic approach, tailoring treatment plans to meet your individual needs and goals. Key factors to consider before surgery include whether preserving fertility is a priority and ensuring the surgeon is accessible for ongoing support and follow-up. It's also important to ask your doctor about their success rates, potential risks, recovery times, and long-term outcomes for patients with similar cases. 

Dr. Ma Li is an internationally recognised endometriosis specialist and minimally invasive gynaecological surgeon based in Singapore, specialising in robotic gynaecological surgery for endometriosis. With a focus on fertility-preserving treatments, Dr. Ma Li offers comprehensive care to help manage the condition. Learn more about Dr. Ma Li’s approach and book a consultation at Dr. Ma Li Clinic.

Robotic gynaecological surgery removes endometrial tissue while minimising damage to surrounding organs and preserving fertility. 

How much does Endometriosis Treatment Cost?

In Singapore, the cost of endometriosis treatment depends on factors such as the severity of the condition, the type of treatment, and the chosen clinic. For example, laparoscopic surgery typically costs between SGD 25,000 and SGD 35,000, with variations depending on the complexity and fees. Robotic gynaecological surgery tends to be more expensive due to the specialised technology and expertise involved.

Patients in Singapore may use MediSave to help cover some surgical costs. There may also be private insurance coverage, depending on your insurer and plan. When evaluating the cost of treatment, it’s also important to consider the long-term benefits, such as improved quality of life and the potential for fertility preservation.

What to Expect After Endometriosis Treatment

After treatment, particularly surgery, many women experience significant relief from pain, reduced menstrual cramps, and less discomfort during intercourse. This leads to less dependence on pain medications and an improved quality of life. Minimally invasive surgeries such as robotic gynaecological surgery offer faster recovery and quick healing, allowing patients to return to their normal activities as soon as possible. 

As endometriosis is a long-term condition, follow-up appointments are essential to monitor progress, manage symptoms, and ensure long-term health and fertility goals are met. Regular check-ups are important to detect recurrence of endometrial tissue and adjust treatment plans as required. 

Conclusion

For those with severe symptoms or who wish to conceive, endometriosis treatment is essential for pain relief, preserving fertility, and improving overall quality of life. Those who suffer from this condition should be aware that there are various treatment options available, such as robotic gynaecological surgery. By effectively removing endometrial tissue, these treatment options provide significant pain relief and can help preserve fertility.

If you're experiencing symptoms of endometriosis, seeking treatment as soon as possible is crucial. Early intervention can help manage the condition while significantly reducing debilitating symptoms and improving quality of life. 

Frequently Asked Questions 

Can endometriosis be permanently treated?

While there's no cure for endometriosis, the symptoms can be significantly reduced through various treatments, including medication and surgery. 

Is endometriosis a serious problem?

Endometriosis is a chronic condition that causes tissue similar to the uterine lining to grow outside the uterus. This tissue can form adhesions and cysts, and can also damage organs. Left untreated, it can cause serious complications. 

Can endometriosis be cancerous?

Although they may sound similar, endometriosis and endometrial cancer are very different conditions. Endometriosis is not cancer, and having endometriosis does not necessarily lead to endometrial cancer. 

Can endometriosis cause weight gain?

Yes, people with endometriosis may gain weight from fluid retention. Hormonal fluctuations and medication side effects may also contribute to weight gain. Speak to your doctor if you are experiencing symptoms such as weight gain. 

References

  1. Chong, C. (2022, March 2). Menstrual pain could be endometriosis; affects 1 in 10 females in child-bearing years in S'pore. The Straits Times. Retrieved from: https://www.straitstimes.com/singapore/menstrual-pain-could-be-endometriosis-affects-1-in-10-women-in-child-bearing-years-here
  2. Mayo Clinic. (n.d.). Endometriosis - Symptoms and causes. Mayo Clinic. Retrieved from: https://www.mayoclinic.org/diseases-conditions/endometriosis/symptoms-causes/syc-20354656
  3. BMC Medicine (2023). Shining a light on endometriosis: time to listen and take action. BMC medicine, 21(1), 107. Retrieved from: https://doi.org/10.1186/s12916-023-02820-y
  4. Harvard Health Publishing. (2024, March 26). Foods that fight inflammation. Harvard Health. Retrieved from: https://www.health.harvard.edu/staying-healthy/foods-that-fight-inflammation
  5. Ferreira, H., Ferreira, J. C., & Fernandes, R. C. (2023). Impact of surgical experience on outcomes of robotic gynecologic surgery: A retrospective study. Revista da Associação Médica Brasileira, 69(10), 1443–1448. Retrieved from: https://www.scielo.br/j/ramb/a/XYdLnbxPMG8nNPR5XRV3hMs/
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